Canine parainfluenza virus infection is a respiratory infectious disease of dogs caused by canine parainfluenza virus, characterized by coughing, runny nose and fever. It often suddenly occurs, with coughs of different frequencies and degrees, as well as varying degrees of decreased appetite and fever, followed by serous, mucous or even purulent nasal discharge. It can often recover naturally in 3 to 7 days. After secondary infection, coughing can last for several weeks or even lead to death.
In addition to secretions in the respiratory tract, there are inflammatory lesions in the tonsils, trachea and bronchi. Sometimes petechiae can be seen in the lungs. Histological examination shows a large number of monocytes and neutrophils infiltrating under the mucosa of the above parts. When co-infected with mycoplasma or Bordetella bronchiseptica, the condition is aggravated. It is reported that this disease can cause acute encephalomyelitis and hydrocephalus. After dogs are infected, they may show symptoms such as hind limb paralysis and ataxia. Sick dogs can support their bodies with their hind limbs, but cannot walk. The knee joint and gastrocnemius tendon reflex and proprioception are not sensitive.